{"id":1459,"date":"2015-08-08T01:01:32","date_gmt":"2015-08-07T22:01:32","guid":{"rendered":"http:\/\/kadinvehastaliklari.com\/?p=1459"},"modified":"2019-10-23T19:08:38","modified_gmt":"2019-10-23T16:08:38","slug":"alpha-fetoprotein-afp","status":"publish","type":"post","link":"http:\/\/daginiktopuz.com\/alpha-fetoprotein-afp\/","title":{"rendered":"Alpha-Fetoprotein (AFP) Nedir?"},"content":{"rendered":"<p style=\"text-align: justify;\">Alpha-fetoprotein (AFP) g\u00fcn\u00fcm\u00fczde tarama testi olarak kullan\u0131l\u0131r. \u00d6zellikle son y\u0131llarda n\u00f6ral t\u00fcp defektlerinin (sipina bifida- histosefali-meningomiyosel) taranmas\u0131nda kullan\u0131lan bir testtir. T\u00fcrkiye n\u00f6ral t\u00fcp defektlerinin s\u0131k g\u00f6r\u00fcld\u00fc\u011f\u00fc bir \u00fclkedir. Bu nedenle bu tarz tarama testleri sa\u011fl\u0131kl\u0131 bebeklerin d\u00fcnyaya gelebilmesi a\u00e7\u0131s\u0131ndan son derece k\u0131ymetlidir.<\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_46 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\">\u0130&ccedil;indekiler<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"ez-toc-toggle-icon-1\"><label for=\"item-651ee4d275b73\" aria-label=\"Table of Content\"><span style=\"display: flex;align-items: center;width: 35px;height: 30px;justify-content: center;direction:ltr;\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/label><input  type=\"checkbox\" id=\"item-651ee4d275b73\"><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"http:\/\/daginiktopuz.com\/alpha-fetoprotein-afp\/#Alpha-Fetoprotein_AFP_nedir\" title=\"Alpha-Fetoprotein (AFP) nedir?\">Alpha-Fetoprotein (AFP) nedir?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"http:\/\/daginiktopuz.com\/alpha-fetoprotein-afp\/#Alpha-Fetoprotein_AFP_testi_ne_zaman_yapilir\" title=\"Alpha-Fetoprotein (AFP) testi ne zaman yap\u0131l\u0131r?\">Alpha-Fetoprotein (AFP) testi ne zaman yap\u0131l\u0131r?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"http:\/\/daginiktopuz.com\/alpha-fetoprotein-afp\/#AFP_testi_neden_yapilir\" title=\"AFP testi neden yap\u0131l\u0131r?\">AFP testi neden yap\u0131l\u0131r?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"http:\/\/daginiktopuz.com\/alpha-fetoprotein-afp\/#AFP_degeri_hangi_durumlarda_duser\" title=\"AFP de\u011feri hangi durumlarda d\u00fc\u015fer.\">AFP de\u011feri hangi durumlarda d\u00fc\u015fer.<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"http:\/\/daginiktopuz.com\/alpha-fetoprotein-afp\/#AFP_hangi_durumlarda_yukselir\" title=\"AFP hangi durumlarda y\u00fckselir?\">AFP hangi durumlarda y\u00fckselir?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"http:\/\/daginiktopuz.com\/alpha-fetoprotein-afp\/#AFP_duzeyi_yuksek_cikarsa_ne_yapilir\" title=\"AFP d\u00fczeyi y\u00fcksek \u00e7\u0131karsa ne yap\u0131l\u0131r?\">AFP d\u00fczeyi y\u00fcksek \u00e7\u0131karsa ne yap\u0131l\u0131r?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"http:\/\/daginiktopuz.com\/alpha-fetoprotein-afp\/#AFP_sonuclarinin_yanlis_yorumlanmasina_neden_olabilecek_durumlar\" title=\"AFP sonu\u00e7lar\u0131n\u0131n yanl\u0131\u015f yorumlanmas\u0131na neden olabilecek durumlar.\">AFP sonu\u00e7lar\u0131n\u0131n yanl\u0131\u015f yorumlanmas\u0131na neden olabilecek durumlar.<\/a><\/li><\/ul><\/nav><\/div>\n<h3 style=\"text-align: justify;\"><span class=\"ez-toc-section\" id=\"Alpha-Fetoprotein_AFP_nedir\"><\/span><strong>Alpha-Fetoprotein (AFP) <\/strong><strong>nedir?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p style=\"text-align: justify;\">K\u0131saca AFP olarak isimlendirilir. Rahim i\u00e7indeki bebe\u011fin karaci\u011ferinin \u00fcretti\u011fi bir proteindir. Ne i\u015fe yarad\u0131\u011f\u0131 hen\u00fcz net olarak a\u00e7\u0131klanamam\u0131\u015ft\u0131r. AFP bebe\u011fin kan\u0131na, oradan amniyotik s\u0131v\u0131ya ve anne kan\u0131na ge\u00e7er. Bu nedenle anne kan\u0131ndaki de\u011ferine bakarak bebek hakk\u0131nda bilgi edinilebilir.<\/p>\n<h3 style=\"text-align: justify;\"><span class=\"ez-toc-section\" id=\"Alpha-Fetoprotein_AFP_testi_ne_zaman_yapilir\"><\/span><strong>Alpha-Fetoprotein (AFP) <\/strong><strong>testi ne zaman yap\u0131l\u0131r?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p style=\"text-align: justify;\">Gebe kad\u0131n 16. ve 20. gebelik haftalar\u0131 aras\u0131nda ise test yap\u0131labilir. \u0130deal test zaman\u0131 16-18. gebelik haftalar\u0131d\u0131r. T\u00fcm gebelerde de\u011ferlendirilmesi gereken bir parametredir. Anneden kan al\u0131narak AFP de\u011ferine bak\u0131l\u0131r.<\/p>\n<h3 style=\"text-align: justify;\"><span class=\"ez-toc-section\" id=\"AFP_testi_neden_yapilir\"><\/span><strong>AFP testi neden yap\u0131l\u0131r?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p style=\"text-align: justify;\">AFP bebe\u011fin beyin, omurilik gibi organlar\u0131nda geli\u015fen bir tak\u0131m hastal\u0131klar\u0131 taramada kullan\u0131l\u0131r. Halk\u0131n s\u0131rt a\u00e7\u0131kl\u0131\u011f\u0131 olarak tan\u0131mlad\u0131\u011f\u0131 sipina bifida ya da bebe\u011fin kafatas\u0131n\u0131n bir k\u0131sm\u0131n\u0131n geli\u015fmedi\u011fi anensefali gibi durumlar hakk\u0131nda hekimlere ipucu verir.<\/p>\n<p style=\"text-align: justify;\"><strong>AFP\u2019nin; <\/strong>15\u201318. gebelik haftalar\u0131 aras\u0131ndaki normal de\u011ferleri 1 &#8211; 2.5 MoM normal kabul edilir. Elde elden de\u011fer normal ise ileri testlere gerek yoktur. Ancak MS-AFP d\u00fc\u015f\u00fck ya da y\u00fcksek ise bebek hakk\u0131nda daha fazla bilgi edinmek i\u00e7in farkl\u0131 testlere (USG ve amniosentez) ihtiya\u00e7 vard\u0131r.<\/p>\n<h3 style=\"text-align: justify;\"><span class=\"ez-toc-section\" id=\"AFP_degeri_hangi_durumlarda_duser\"><\/span><strong>AFP de\u011feri hangi durumlarda d\u00fc\u015fer.<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p style=\"text-align: justify;\">AFP de\u011feri 1 MoM\u2019un alt\u0131nda ise Down\u2019s sendromundan \u015f\u00fcphelenilir.<\/p>\n<h3 style=\"text-align: justify;\"><span class=\"ez-toc-section\" id=\"AFP_hangi_durumlarda_yukselir\"><\/span><strong>AFP hangi durumlarda y\u00fckselir?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p style=\"text-align: justify;\">Bebeklerde herhangi bir anomali varl\u0131\u011f\u0131nda AFP y\u00fckselir.<\/p>\n<ul style=\"text-align: justify;\">\n<li>N\u00f6ral t\u00fcp defektlerinde (beyin, omirilik gibi organlarda a\u00e7\u0131kl\u0131k, geli\u015fmeme vb durumlar) y\u00fckselir.<\/li>\n<li>Bebeklerde b\u00f6breklerin geli\u015fmedi\u011fi durumlarda y\u00fckselir.<\/li>\n<li>\u0130drar yollar\u0131 ile ilgili bir hastal\u0131k durumunda y\u00fckselir.<\/li>\n<li>Bebe\u011fin suyunun azald\u0131\u011f\u0131 (oligohidroamnios) durumlarda y\u00fckselir.<\/li>\n<li>Bebe\u011fin sindirim sistemindeki sorunlarda da (t\u0131kan\u0131kl\u0131k gibi) y\u00fckselir.<\/li>\n<li>Bebek anne karn\u0131nda \u00f6ld\u00fc ise y\u00fckselir.<\/li>\n<\/ul>\n<h3 style=\"text-align: justify;\"><span class=\"ez-toc-section\" id=\"AFP_duzeyi_yuksek_cikarsa_ne_yapilir\"><\/span><strong>AFP d\u00fczeyi y\u00fcksek \u00e7\u0131karsa ne yap\u0131l\u0131r?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p style=\"text-align: justify;\">E\u011fer elde edilen de\u011fer 2.5 MoM dan daha y\u00fcksek ise, detayl\u0131 ultrason denilen y\u00f6ntemle bebek incelenir. AFP de\u011feri y\u00fckseldik\u00e7e bebekte herhangi bir hastal\u0131k olma olas\u0131l\u0131\u011f\u0131 artar. E\u011fer ultrason incelemesinde bebekte herhangi bir anomaliye rastlanmazsa, amniyosentez yap\u0131l\u0131r. Amniyosentezden \u00e7\u0131kan sonu\u00e7 bize bebe\u011fin sa\u011fl\u0131\u011f\u0131 hakk\u0131nda en do\u011fru bilgiyi verecektir.<\/p>\n<h3 style=\"text-align: justify;\"><span class=\"ez-toc-section\" id=\"AFP_sonuclarinin_yanlis_yorumlanmasina_neden_olabilecek_durumlar\"><\/span><strong>AFP sonu\u00e7lar\u0131n\u0131n yanl\u0131\u015f yorumlanmas\u0131na neden olabilecek durumlar.<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<ul>\n<li style=\"text-align: justify;\">Obesite; MS-AFP\u2019nin azalmas\u0131na neden olabilir.<\/li>\n<li style=\"text-align: justify;\">Irk: MS-AFP seviyesi Afrika\u2019l\u0131larda Asya\u2019l\u0131lara g\u00f6re % 10 ila % 15 daha y\u00fcksektir.<\/li>\n<li style=\"text-align: justify;\">Ins\u00fcline ba\u011f\u0131ml\u0131 diyabet: MS-AFP\u2019nin azalmas\u0131na neden olur.<\/li>\n<li style=\"text-align: justify;\">\u0130kiz ya da \u00fc\u00e7\u00fcz gebelikte AFP d\u00fczeyi artar.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Alpha-fetoprotein (AFP) g\u00fcn\u00fcm\u00fczde tarama testi olarak kullan\u0131l\u0131r. \u00d6zellikle son y\u0131llarda n\u00f6ral t\u00fcp defektlerinin (sipina bifida- histosefali-meningomiyosel) taranmas\u0131nda kullan\u0131lan bir testtir. T\u00fcrkiye n\u00f6ral t\u00fcp defektlerinin s\u0131k g\u00f6r\u00fcld\u00fc\u011f\u00fc bir \u00fclkedir. Bu nedenle bu tarz tarama testleri sa\u011fl\u0131kl\u0131 bebeklerin d\u00fcnyaya gelebilmesi a\u00e7\u0131s\u0131ndan son derece k\u0131ymetlidir. Alpha-Fetoprotein (AFP) nedir? K\u0131saca AFP olarak isimlendirilir. Rahim i\u00e7indeki bebe\u011fin karaci\u011ferinin \u00fcretti\u011fi bir &hellip;<\/p>\n","protected":false},"author":48,"featured_media":1462,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[26],"tags":[152,1342,2371,2400,3001],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.10 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>alpha-fetoprotein (AFP)<\/title>\n<meta name=\"description\" content=\"alpha-fetoprotein (AFP), Alpha-Fetoprotein (AFP) testi ne zaman yap\u0131l\u0131r?, AFP testi neden yap\u0131l\u0131r?, AFP de\u011feri hangi durumlarda d\u00fc\u015fer.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/daginiktopuz.com\/alpha-fetoprotein-afp\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta 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